In Why We Get Sick, Dr. Benjamin Bikman, a metabolic scientist and professor at Brigham Young University, delivers a persuasive case that insulin resistance drives many modern chronic diseases. Drawing from his research in bioenergetics, Bikman argues that this condition—marked by elevated insulin levels and reduced cellular responsiveness—underlies not only diabetes but also heart disease, cancer, infertility, and Alzheimer’s. Inspired by insights from The Wellness By Design Project podcast (April 2023), this review explores Bikman’s compelling thesis and practical solutions.
Bikman demystifies insulin as the hormone governing energy use and storage, explaining how insulin resistance disrupts this process differently across tissues. For example, while muscle cells may resist insulin, ovaries may overproduce estradiol, contributing to polycystic ovary syndrome (PCOS). In the brain, declining insulin function limits glucose access, elevating Alzheimer’s risk—a factor Bikman suggests may outweigh age. He identifies stress (high cortisol), sleep deprivation, inflammation, and excessive linoleic acid (from processed oils like soy or canola) as primary causes, offering a clear framework for understanding this metabolic crisis.
The book’s strength lies in its actionable advice. Bikman advocates low-carbohydrate diets, structured fasting, and resistance training to restore insulin sensitivity, cautioning against pitfalls like sugary post-workout drinks or overeating during fasting windows. His engaging style makes complex science accessible, empowering readers to take charge of their health. However, the heavy focus on insulin resistance as a universal culprit may oversimplify other disease factors, and more guidance on navigating cultural or social barriers to dietary changes would enhance practicality.
Why We Get Sick is a thought-provoking, evidence-based guide for anyone seeking to combat chronic disease or optimize metabolic health. Bikman’s insights, blending rigorous science with practical strategies, make this a must-read for biohackers, health enthusiasts, or those managing conditions like obesity or PCOS. Explore more at benbikman.com or through Bikman’s podcast, The Metabolic Classroom.