Hot flashes are not simply the price of admission to menopause. They are a dynamic signal of neuroendocrine stress, metabolic inflexibility, and sympathetic overdrive—often amplified by inefficient catecholamine clearance. Emerging evidence from Jerilynn Prior’s work with oral micronized progesterone 300 mg, alongside the arrival of neurokinin-3 (NK3) receptor antagonists like fezolinetant, now allows a more nuanced and mechanistic approach to vasomotor symptoms (VMS) that goes far beyond “give estrogen or not.” Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial | Scientific Reports
hot flashes
Can You Use TOO Much Progesterone?
Too much progesterone, how much is too much? During the last trimester of pregnancy, women can reach levels of progesterone in the serum as high as 200-300 ng/ml and more. During the luteal phase, getting to a level of 20 to 30 ng/ml is usual. Most women feel amazing during the last three months of … Read more