Progesterone and the mTOR Aging System

person holding a stress ball

Unraveling how and why we age is a research focus.  We are still captivated by the Ponce de Leon promise of the Fountain of Youth.  An enzyme system named mTOR (mammalian or mechanistic target of rapamycin) was identified in mouse studies as a significant aging mechanism.  Inhibition of mTOR by rapamycin, found in bacteria species: S. cerevisiae, C. elegans, … Read more

The Tyranny of Flow Chart Medicine

crop doctor with stethoscope in hospital

When I started my career as a pharmacist many years ago, one of my mentors warned me that pharmacists were expendable. We would soon be replaced by vending machines. Indeed, I witnessed the first of these being installed in hospitals to dispense commonly used drugs on the floors. Medical practitioners are equally expendable. With FDA … Read more

Symptoms of Progesterone Deficiency

woman holding her head

Ignored by many practitioners, progesterone is meant to be abundant.  Much confusion can be attributed to this common portrayal of the menstrual cycle: While the rise and fall of hormones is depicted correctly, this graphic implies that the only significant level of progesterone occurs in the 2nd half of the cycle during the luteal phase.  … Read more

A LIFETIME OF PROGESTERONE

man and woman jogging

Progesterone is essential for a long and healthy life. The body’s need for progesterone spans an entire lifetime, from being essential for conception to offering resilience and gentle aging. In women, progesterone is secreted in the second half of the menstrual cycle from the released corpus luteum and, in much greater quantity, by the placenta … Read more