Why DHT Blockers Cause Insomnia & Anxiety: How Progesterone Solves the 5-Alpha Paradox

Infographic showing how 5-alpha reductase converts progesterone into allopregnanolone for sleep and mood, and how DHT blockers disrupt this pathway.

In the pursuit of optimized health, hormonal balance, and aesthetic preservation, the enzyme 5-alpha reductase (5-AR) often plays the role of the villain. It is the biological catalyst responsible for converting testosterone into dihydrotestosterone (DHT), the potent androgen blamed for male pattern baldness, acne, and prostate enlargement. Consequently, a massive market has emerged for “DHT blockers”—ranging from pharmaceutical heavyweights like finasteride to natural pantry staples like pumpkin seeds, zinc, and saw palmetto.

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Hormone Therapy for Pain Management

symbolic image of the interplay between hormones and pain

Hormone therapy for pain management is a topic not well documented. In this article, we’ll attempt to fill in those gaps. Hormones are powerful chemical messengers in the body, influencing everything from mood to metabolism. One of their lesser-known but critical roles is in pain management. By modulating pain perception, inflammation, and stress responses, hormones can significantly impact how we experience and cope with pain. This article explores the key hormones involved in pain management, their mechanisms, and emerging therapies like oxytocin and hormone replacement therapy (HRT) that offer hope for more effective, sustainable pain relief.

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